Education:

Hacettepe University, English Faculty of Medicine (1983-1990)
Hacettepe University, Faculty of Medicine, Internal Medicine (Specialization, 1990-1995)
Hacettepe University, Faculty of Medicine, Gastroenterology (1995-1997)

Associate Professorship: 2002
Professorship: 2013

Foreign Language: English

Professional Experience:

Aktif International Yalova (2025 – Present)
Private Istanbul Oncology Hospital (2019 – 2025)
Private Toprak Hospital (2017 – 2019)
Private Adatıp Sakarya Hospital (2016 – 2017)

Medical Areas of Interest:

Esophageal cancer, Reflux disease, Gastritis, Stomach ulcer, Cancer, Gallbladder Obstructive diseases of the gallbladder and bile ducts, obstructive jaundice, liver diseases, acute and chronic hepatitis, cirrhosis, celiac disease, ulcerative colitis and Crohn’s disease, colorectal disease of the colon and colon cancers. Acute and chronic pancreatitis, pancreatic cysts and pancreatic cancers.

Interventional endoscopic procedures performed;

Endoscopic reflux treatments
- ARMA procedure
- GEDX procedure
Endoscopic weight loss procedures
- Gastric balloon
- Fundal ablation (GFMA)
- POSE-2
- ESG
Gastroscopy and colonoscopy
- Routine procedures
- Polypectomy – removal of polyps
  - EMR
  - ESD
  - Band-assisted EMR
  - EFTR
- For esophageal, gastric, duodenal, and colonic strictures
  - Balloon dilation
  - Metal stent placement
Esophagus
- Variceal band ligation
- Balloon or stent treatment for esophageal strictures
- Coil placement for fundal varices under endoscopic ultrasound guidance
Percutaneous endoscopic feeding tube placements
- PEG
- PEJ
Endoscopic ultrasound
- Diagnostic endoscopic ultrasound
  - Endoscopic diagnosis of subepithelial lesions in the esophagus, stomach, and colon (both radial and linear echoendoscopes are available)
- Liver biopsy
- Pancreatic biopsy
- Drainage of pancreatic cysts and pseudocysts
- Celiac nerve blocks
ERCP-related procedures
- Removal of bile duct stones
- Treatment of bile duct strictures with stenting
- Biopsy of bile duct tumors via cholangioscopy
- Diagnostic cholangioscopy
- ERCP with double-balloon enteroscopy
- ERCP with endosonography-guided appointment

Professional Memberships:

Turkish Gastroenterology Association
Internal Medicine Association

Academic Publications:

Genotype distribution of chronic hepatitis B and hepatitis C patients and investigation of the resistance patterns in hepatitis B cases. Kalayci R, Altindiş M, Gülamber G, Demirtürk N, Akcan Y, Demirdal T. Mikrobiyol Bul. 2010 Apr; 44 (2): 237-43. Turkish.

Does Helicobacter pylori-induced inflammation of gastric mucosa determine the severity of symptoms in functional dyspepsia? Turkkan E, Uslan I, Acarturk G, Topak N, Kahraman A, Dilek FH, Akcan Y, Karaman O, Colbay M, Yuksel S. J Gastroenterol. 2009; 44 (1): 66-70.

Evaluation of risk factors and seroprevalence of hepatitis B and C in diabetic patients in Kutahya, Turkey. Gulcan A, Gulcan E, Toker A, Bulut I, Akcan Y. J Investig Med. 2008 Aug; 56 (6): 858-63.

The Effects of Weight Loss on Normal Transaminase Levels in Obese Patients. Uslan I, Acarturk G, Karaca E, Albayrak R, Yuksel S, Colbay M, Karaman O, Akcan Y. Am J Med Sci. 2007 Nov; 334 (5): 327-330.

Prevalence of Helicobacter pylori in symptomatic patients and detection of clarithromycin resistance using melting curve analysis . Kaya, AD; Ozturk, CE; Akcan, Y, et al. CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL MAY-JUN 2007, 68 (3): 151-160.

The comparison of dexmedetomidine and midazolam used for sedation of patients during upper endoscopy: A prospective, randomized study. Demiraran Y, Korkut E, Tamer A, Yorulmaz I, Kocaman B, Sezen G, Akcan Y. Can J Gastroenterol. 2007 Jan; 21 (1): 25-9.

Two successive pregnancies after ursodeoxycholic acid therapy in a previously infertile woman with antimitochondrial antibody-negative primary biliary cirrhosis. Korkut E, Kisacik B, Akcan Y, Belenli O, Bicik Z, Yucel O. Fertil Steril. 2005 Mar; 83 (3): 761-3.

Erdogmus B, Yazici B, Ozdere BA, Akcan Y.Clinical and ultrasonographical findings in patients with multiseptate gallbladder. Tohoku J Exp Med. 2004 Nov; 2004 (3): 215-9.

Alper M, Akcan Y, Belenli OK, Cukur S, Aksoy KA, Suna M.Gastric pseudolipomatosis, usual or unusual? Re-evaluation of 909 endoscopic gastric biopsies. World J Gastroenterol. 2003 Dec; 9 (12): 2846-8.

Akcan Y, Bayraktar Y, Arslan S, Van Thiel DH, Zerrin BC, Yildiz O. The importance of serial measurements of cytokine levels for the evaluation of their role in pathogenesis in familial Mediterraean fever. Eur J Med Res. 2003 Jul 31; 8 (7): 304-6.

Caglar M, Sari O, Akcan Y. Prediction of therapy response to interferon-alpha in chronic viral hepatitis-B by liver and hepatobiliary scintigraphy. Ann Nucl Med. 2002 Nov; 16 (7): 511-4.

Bicik, Y. Akcan, B. Uğur. Effect of verapamil sustained relase on the sympathetic nervous system response to isometric stress in patients with Essential hypertension: a pilot study in Turkish patients. Current Therapeutic Research-Clinical And Experimental 2001; 62 (8): 595-600.

İdris Koçak, Yusuf Akcan, Cazip Üstün, Cem Demirel, Lügen Cengiz, F. Filiz Yanık. Helicobacter pylori seropositivity in patients with Hyperemesis Gravidarum. International Journal of Obstetrics & Gynecology 1999: 66 (3): 251-4.

Idris Koçak, Cazip Üstün, Yusuf Akcan, İlkser Akpolat. Reduction of adhesion formation with cross- linked hyaluronic acid after peritoneal surgery in rats. Fertil Steril 1999; 7 (5): 873-878.

Güvener N, Akcan Y, Paksoy I, Soylu AR, Aydin M, Arslan S, Gedik O. Helicobacter pylori associated gastric pathology in patients with type II diabetes mellitus and its relationship with gastric emptying: The Ankara study. Experimantel and clinical endocrinology & diabetes 1999; 107: 172-176.

Akcan Y, Tuncer S, Unal S, Sokmensuer C, Haznedaroglu CI, Arslan S. Familial Mediterranean Fever No Role of Mycobacterium Tuberculosis in Ten Patients. Eur J Med Res 1999 Apr 27; 4 (4): 161-164.

Akcan Y, Tuncer AS, Hayran M, Sungur A, Unal S. Use of PCR in disseminated tuberculosis in bone marrow and liver biopsy specimens and correlation with pathological and clinical diagnosis. Scand J Infect Dis 1997; 29 (3): 271-4.

TGF-beta1 is the possible shared pathogenetic factor on a patient with muscular dystrophy and congenital hepatic fibrosis. Gulcan E, Helvaci MR, Aksoy KA, Gulcan A, Akcan Y. Med Hypotheses. 2006; 67 (2): 428-9. Epub 2006 Apr 24.

Akcan Y, Kavak A, Sertbas Y, Olut AI, Korkut E, Bicik Z, Kisacik B.The low seropositivity of hepatitis B virus in vitiligo patients. J Eur Acad Dermatol Venereol. 2006 Jan; 20 (1): 110-1.

Kavak A, Akcan Y, Korkmaz U. Hair repigmentation in a hepatitis C patient treated with interferon and ribavirin. Dermatology. 2005; 211 (2): 171-2.

Erdogmus B, Yazici B, Akcan Y, Ozdere BA, Korkmaz U, Alcelik A.Latent fatality due to hydatid cyst rupture after a severe cough episode. Tohoku J Exp Med. 2005 Mar; 205 (3): 293-6.

Alper M, Akcan Y, Belenli O.Large pedinculated antral hyperplastic gastric polyp traversed the bulbus causing outlet obstruction and iron deficiency anemia: endoscopic removal. World J Gastroenterol. 2003 Mar; 9 (3): 633-4.

Settbas Y, Alper M, Akcan Y, Gurbuz Y, Oksuz S.Massive gastrointestinal tuberculosis in a young patient without immunosuppression. World J Gastroenterol. 2003 Oct; 9 (10): 2382-4.

Akcan Y, Arslan S. Aspiration sclerotherapy; A simple endoscopic modification for oesophageal variceal sclerotherapy. Endoscopy 1998; 30: S57-8.

Emel Erkek, Ayşen Karaduman, Yusuf AKCAN, Cenk Sökmensüer, Gül Bükülmez. Psoriasis asssociated with HCV and exacerbated by interferon alphha: complete clearance with acitretin during interferon alpha treatment for chronic active hepatitis. Dermatology. 2000; 201 (2): 180-181.

Yusuf AKCAN, Sibel ERSAN, Murat ALPER, Zerrin BİCİK, Necip Aytuğ. The transmission of Helicobacter pylori via exposure to common sources outweighs the person to person contact among spouses in developing countries. Am J Gastroenterol 2000; 95 (1): 317-319.

Soylu AR, Özcebe OI, Haznedaroğlu IC, Kadayıfçı A, Büyükaşık Y, Akcan Y. Seroprevalance of hepatitis B virus, hepatitis C virus, and human immundeficiency virus antibodies in Turkish patients with hereditary coagulation factor deficiencies. Vox Sanguinis 1997; 73: 54.

AR Soylu, G. Öksüzoğlu, G.Tatar, Y. Akcan, A.Gürlek. The effect of Seasons on variceal bleeding in patients with cirrhosis. Am J Gastroenterol, 91(4), 823, 1996.

Ovarian relaps and cutaneous involvement in a case of acute lymphoblastic leukemia. Haluk Demiroğlu, Osman Ilhami Özcebe, Yusuf AKCAN, Oktay Özdemir, Ibrahim haznedaroğlu, Semra Dündar. Acta Haematol 1994; 92: 56.

Safe liver biopsy in a patient with chronic hepatitis C under continuous ambulatory peritoneal dialysis treatment. Bicik Z, Akcan Y, Korkut E, Korkmaz U, Sertbas Y, Caliskan S. Indian J Gastroenterol. 2005 Mar-Apr; 24 (2): 87-8.

Belenli OK, Akcan Y, Alper M.Micropneumatosis coexistent with Helicobacter pylori and its improvement. Indian J Gastroenterol. 2003 Sep-Oct; 22 (5): 191-2.